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Lee Lab

Laboratory of Regenerative Medicine

이미지 제공: bharath kumar

부산의대 재생의학 연구실

Laboratory of Regenerative Medicine

이미지 제공: Pawel Czerwinski

Welcome to Lee Laboratory

Our aims are to discern stem cells regulation for the cure of cancer

ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.

Publication 개요.jpg

Recent News

Inhalable nanohybrid of delpazolid enhances antimicrobial host defense against mycobacterial pulmonary infection.

4월 22일

CD127+ Natural Killer Cells Represent a Distinct, Interleukin-15-Independent and Thymus-Independent Subset in Mice.

3월 14일

월간인물 3월호

월간인물 3월호

월간인물 3월호

3월 5일

Mechanical Stimuli-Induced Manipulation of Malignant Behavior in Bioprinted Cancer Microtissues via PI3K/NF-κB Activation.

3월 3일

우수연 박사 졸업

우수연 박사 졸업

우수연 박사 졸업

2월 20일

COPG1 Is a Selectively Essential Regulator of Cancer Progression and Chemoresistance via Redox Modulation and AKT Signaling.

2월 10일

Exploring the Angiogenic Potential of Skin Patches with Endothelial Cell Patterns Fabricated via In-Bath 3D Bioprinting Using Light-Activated Bioink for Enhanced Wound Healing.

2월 3일

Characterization of Korean Colorectal Cancer Reveals Novel Driver Gene and Clinically Relevant Mutations.

1월 8일

Polydopamine-Coated Surfaces Promote Adhesion, Migration, Proliferation, Chemoresistance, Stemness, and Epithelial-Mesenchymal Transition of Human Prostate Cancer Cell Lines In Vitro via Integrin α2β1

1월 8일

AP2M1 Amplification Orchestrates Notch-Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients.

2025년 12월 2일

Global prevalence of seasonal affective disorder by latitude: A systematic review and meta-analysis

2025년 12월 1일

Paroxetine suppresses 27-hydroxycholesterol-induced responses in THP- 1 human monocytic cells by regulating the AKT/mTORC1 pathway.

2025년 10월 21일

HSP90 Inhibition Disrupts 27-Hydroxycholesterol-Induced Inﬂammatory Signaling in Monocytic Cells.

2025년 10월 13일

A Robust Marine Collagen Peptide-Agarose 3D Culture System for In Vitro Modeling of Hepatocellular Carcinoma and Anti-Cancer Therapeutic Development.

2025년 9월 27일

2025년도 한국생명과학회 HK 학술상 수상국생명과학회 HK 학술상 수상

2025년도 한국생명과학회 HK 학술상 수상국생명과학회 HK 학술상 수상

2025년도 한국생명과학회 HK 학술상 수상국생명과학회 HK 학술상 수상

2025년 8월 22일

Proteomic analysis reveals inhibition of mevalonate and Glycolysis pathways in hepatocytes by 27-hydroxycholesterol

2025년 8월 4일

부산대 의과대학·의학연구원 「2024년 올해의 연구자상」 시상

부산대 의과대학·의학연구원 「2024년 올해의 연구자상」 시상

부산대 의과대학·의학연구원 「2024년 올해의 연구자상」 시상

2025년 2월 1일

Uncovering NK cell sabotage in gut diseases via single cell transcriptomics

2025년 1월 3일

Silencing of Epidermal Growth Factor-like Domain 8 Promotes Proliferation and Cancer Aggressiveness in Human Ovarian Cancer Cells by Activating ERK/MAPK Signaling Cascades

2024년 12월 31일

은성의료재단, 부산의대 올해의 연구자상서 ‘은성의학상’ 시상

2024년 12월 20일

부산대 의과대학·의학연구원, '올해의 연구자상' 시상

2024년 12월 20일

은성의료재단, 부산의대 올해의 연구자상 '은성의학상' 시상

2024년 12월 20일

부산대 의과대학·의학연구원 「2024년 올해의 연구자상」시상

2024년 12월 20일

ERRα is dispensable for hematopoietic stem cell function in the bone marrow

ERRα is dispensable for hematopoietic stem cell function in the bone marrow

ERRα is dispensable for hematopoietic stem cell function in the bone marrow

2024년 12월 20일

TGFβ2-Driven Ferritin Degradation and Subsequent Ferroptosis Underlie Salivary Gland Dysfunction in Postmenopausal Conditions

2024년 12월 1일

Functional Role of UNC13D in Immune Diseases and Its Therapeutic Applications

2024년 10월 14일

27-Hydroxycholesterol negatively affects the function of bone marrow endothelial cells in the bone marrow

27-Hydroxycholesterol negatively affects the function of bone marrow endothelial cells in the bone marrow

27-Hydroxycholesterol negatively affects the function of bone marrow endothelial cells in the bone marrow

2024년 9월 29일

3D engineering of diseased blood vessels for integrative in vitro-in silico mechanobiology study

2024년 9월 26일

Blockade of mTORC1 via rapamycin suppresses 27-hydroxycholestrol-induced inflammatory responses

Blockade of mTORC1 via rapamycin suppresses 27-hydroxycholestrol-induced inflammatory responses

Blockade of mTORC1 via rapamycin suppresses 27-hydroxycholestrol-induced inflammatory responses

2024년 9월 26일

Functional Role of UNC13D in Immune Diseases and Its Therapeutic Applications

2024년 9월 24일

Recycling machinery of integrin coupled with focal adhesion turnover via RAB11-UNC13D-FAK axis for migration of pancreatic cancer cells

2024년 8월 1일

A Marine Collagen-Based 3D Scaffold for In Vitro Modeling of Human Prostate Cancer Niche and Anti-Cancer Therapeutic Discovery

2024년 6월 26일

Body mass index and meniscal tears: Evidence from meta-analysis of observational studies and Mendelian randomization

Body mass index and meniscal tears: Evidence from meta-analysis of observational studies and Mendelian randomization

Body mass index and meniscal tears: Evidence from meta-analysis of observational studies and Mendelian randomization

2024년 6월 21일

Hematopoietic Stem Cells and Their Niche in Bone Marrow

Hematopoietic Stem Cells and Their Niche in Bone Marrow

Hematopoietic Stem Cells and Their Niche in Bone Marrow

2024년 6월 21일

Leukemic Stem Cells and Hematological Malignancies

Leukemic Stem Cells and Hematological Malignancies

Leukemic Stem Cells and Hematological Malignancies

2024년 6월 17일

Advancement in Cancer Vasculogenesis Modeling through 3D Bioprinting Technology

Advancement in Cancer Vasculogenesis Modeling through 3D Bioprinting Technology

Advancement in Cancer Vasculogenesis Modeling through 3D Bioprinting Technology

2024년 5월 1일

김지원(박사과정), 이나령, 이혜진(석박사통합과정) 랩 조인

2024년 3월 1일

의학학술상 수상

의학학술상 수상

의학학술상 수상

2024년 2월 16일

세포기반 인공혈액 기술개발 사업단 현판식

세포기반 인공혈액 기술개발 사업단 현판식

세포기반 인공혈액 기술개발 사업단 현판식

2024년 2월 1일

Vascularization strategies for human skin tissue engineering via 3D bioprinting

2024년 1월 28일

Deciphering head and neck cancer microenvironment: Single-cell and spatial transcriptomics reveals human papillomavirus-associated differences

Deciphering head and neck cancer microenvironment: Single-cell and spatial transcriptomics reveals human papillomavirus-associated differences

Deciphering head and neck cancer microenvironment: Single-cell and spatial transcriptomics reveals human papillomavirus-associated differences

2024년 1월 1일

Association of smoking with amyotrophic lateral sclerosis: A systematic review, meta-analysis, and dose-response analysis

Association of smoking with amyotrophic lateral sclerosis: A systematic review, meta-analysis, and dose-response analysis

Association of smoking with amyotrophic lateral sclerosis: A systematic review, meta-analysis, and dose-response analysis

2024년 1월 1일

Side-Chain Immune Oxysterols Induce Neuroinflammation by Activating Microglia

Side-Chain Immune Oxysterols Induce Neuroinflammation by Activating Microglia

Side-Chain Immune Oxysterols Induce Neuroinflammation by Activating Microglia

2023년 10월 1일

Fish Collagen Peptides Enhance Thymopoietic Gene Expression, Cell Proliferation, Thymocyte Adherence, and Cytoprotection in Thymic Epithelial Cells via Activation of the Nuclear Factor-κB Pathway, Lea

Fish Collagen Peptides Enhance Thymopoietic Gene Expression, Cell Proliferation, Thymocyte Adherence, and Cytoprotection in Thymic Epithelial Cells via Activation of the Nuclear Factor-κB Pathway, Lea

Fish Collagen Peptides Enhance Thymopoietic Gene Expression, Cell Proliferation, Thymocyte Adherence, and Cytoprotection in Thymic Epithelial Cells via Activation of the Nuclear Factor-κB Pathway, Lea

2023년 10월 1일

Predicting prognosis throughthe discovery of specific biomarkers according to colorectal cancer lymph node metastasis

Predicting prognosis throughthe discovery of specific biomarkers according to colorectal cancer lymph node metastasis

Predicting prognosis throughthe discovery of specific biomarkers according to colorectal cancer lymph node metastasis

2023년 7월 31일

The Prognostic Significance of Leukocyte Count on All-Cause and Cardiovascular Disease Mortality: A Systematic Review and Meta-Analysis

The Prognostic Significance of Leukocyte Count on All-Cause and Cardiovascular Disease Mortality: A Systematic Review and Meta-Analysis

The Prognostic Significance of Leukocyte Count on All-Cause and Cardiovascular Disease Mortality: A Systematic Review and Meta-Analysis

2023년 7월 1일

젊은교수 교육상 수상

젊은교수 교육상 수상

젊은교수 교육상 수상

2023년 6월 30일

Atheroma-Relevant 7-Oxysterols Differentially Upregulate Cd14 Expressio

Atheroma-Relevant 7-Oxysterols Differentially Upregulate Cd14 Expressio

Atheroma-Relevant 7-Oxysterols Differentially Upregulate Cd14 Expressio

2023년 6월 1일

Geographical differences of risk of asthma and allergic rhinitis according to urban/rural area: A systematic review and meta-analysis of cohort studies

Geographical differences of risk of asthma and allergic rhinitis according to urban/rural area: A systematic review and meta-analysis of cohort studies

Geographical differences of risk of asthma and allergic rhinitis according to urban/rural area: A systematic review and meta-analysis of cohort studies

2023년 6월 1일

Shear stress induces monocyte/macrophage-mediated inflammation by upregulating cell-surface expression of heat shock proteins

Shear stress induces monocyte/macrophage-mediated inflammation by upregulating cell-surface expression of heat shock proteins

Shear stress induces monocyte/macrophage-mediated inflammation by upregulating cell-surface expression of heat shock proteins

2023년 5월 1일

우박사 졸업1.jpg

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